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1

Safe engineering of CAR T cells for adoptive cell therapy of cancer using long‐term episomal gene transfer

Jin, Chuan, Fotaki, Grammatiki, Ramachandran, Mohanraj, Nilsson, Berith, Essand, Magnus, Yu, Di

Journal:

EMBO Molecular Medicine

Year:

2016

Language:

english

File:

PDF, 1.15 MB

english, 2016

2

Anti-prostate immunotoxins: Cytotoxicity of E4 antibody–pseudomonas exotoxin constructs

Magnus Essand, Ira Pastan

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 96 KB

english, 1998

3

CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

Moa Fransson, Elena Piras, Joachim Burman, Berith Nilsson, Magnus Essand, BinFeng Lu, Robert A Harris, Peetra U Magnusson, Eva Brittebo, Angelica SI Loskog

Journal:

Journal of Neuroinflammation

Year:

2012

Language:

english

File:

PDF, 729 KB

english, 2012

4

Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice

Hillerdal, Victoria, Ramachandran, Mohanraj, Leja, Justyna, Essand, Magnus

Journal:

Year:

2014

Language:

english

File:

PDF, 318 KB

english, 2014

5

Tat-PTD-Modified Oncolytic Adenovirus Driven by the SCG3 Promoter and ASH1 Enhancer for Neuroblastoma Therapy

Jin, Chuan, Yu, Di, Čančer, Matko, Nilsson, Berith, Leja, Justyna, Essand, Magnus

Journal:

Human Gene Therapy

Year:

2013

Language:

english

File:

PDF, 788 KB

english, 2013

6

Allogeneic lymphocyte-licensed DCs expand T cells with improved antitumor activity and resistance to oxidative stress and immunosuppressive factors

Jin, Chuan, Yu, Di, Hillerdal, Victoria, Wallgren, AnnaCarin, Karlsson-Parra, Alex, Essand, Magnus

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2014

Language:

english

File:

PDF, 675 KB

english, 2014

7

Virus-Based Immunotherapy of Glioblastoma

Martikainen, Miika, Essand, Magnus

Journal:

Year:

2019

Language:

english

File:

PDF, 957 KB

english, 2019

8

Radioimmunotherapy of prostatic adenocarcinomas: Effects of 131I-labelled E4 antibodies on cells at different depth in DU 145 spheroids

Magnus Essand, Christina Grönvik, Torbjörn Hartman, Jörgen Carlsson

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 971 KB

english, 1995

9

Ex vivo stimulation of cytomegalovirus (CMV)-specific T cells using CMV pp65-modified dendritic cells as stimulators

Björn Carlsson, Wing-Shing Cheng, Thomas H. Tötterman, Magnus Essand

Journal:

British Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 952 KB

english, 2003

10

GDEP, a new gene differentially expressed in normal prostate and prostate cancer

Pär Olsson, Tapan K. Bera, Magnus Essand, Vasantha Kumar, Paul Duray, James Vincent, Byungkook Lee, Ira Pastan

Journal:

Year:

2001

Language:

english

File:

PDF, 731 KB

english, 2001

11

Generation of cytotoxic T lymphocytes specific for the prostate and breast tissue antigen TARP

Björn Carlsson, Thomas H. Tötterman, Magnus Essand

Journal:

Year:

2004

Language:

english

File:

PDF, 201 KB

english, 2004

12

Adenovirus-mediated CD40 ligand therapy induces tumor cell apoptosis and systemic immunity in the TRAMP-C2 mouse prostate cancer model

Helena Dzojic, Angelica Loskog, Thomas H. Tötterman, Magnus Essand

Journal:

Year:

2006

Language:

english

File:

PDF, 252 KB

english, 2006

13

Characterization of human prostate and breast cancer cell lines for experimental T cell-based immunotherapy

Björn Carlsson, Ole Forsberg, Mats Bengtsson, Thomas H. Tötterman, Magnus Essand

Journal:

Year:

2007

Language:

english

File:

PDF, 189 KB

english, 2007

14

High frequency of prostate antigen-directed T cells in cancer patients compared to healthy age-matched individuals

Ole Forsberg, Björn Carlsson, Per-Uno Malmström, Gustav Ullenhag, Thomas H. Tötterman, Magnus Essand

Journal:

Year:

2009

Language:

english

File:

PDF, 362 KB

english, 2009

15

Radiation sensitization by estramustine studies on cultured human prostatic cancer cells

Solveig Eklöv, Sten Nilsson, Magnus Essand, JÖRgen Carlsson

Journal:

Year:

1992

Language:

english

File:

PDF, 534 KB

english, 1992

16

CD8+T cells against multiple tumor-associated antigens in peripheral blood of midgut carcinoid patients

Sofia Vikman, Valeria Giandomenico, Roberta Sommaggio, Kjell Öberg, Magnus Essand, Thomas H. Tötterman

Journal:

Cancer Immunology, Immunotherapy

Year:

2008

Language:

english

File:

PDF, 550 KB

english, 2008

17

Retention and processing of the monoclonal anti-prostate E4 antibody after binding to prostatic adenocarcinoma DU 145 cells

Magnus Essand, P. Lögdahl, Sten Nilsson, Maria Wartenberg, Helmut Acker, J. Carlsson

Journal:

Cancer Immunology, Immunotherapy

Year:

1996

Language:

english

File:

PDF, 282 KB

english, 1996

18

Strategy for boron neutron capture therapy against tumor cells with over-expression of the epidermal growth factor-receptor

Jörgen Carlsson, Lars Gedda, Christina Grönvik, Torbjörn Hartman, Annelie Lindström, Peter Lindström, Hans Lundqvist, Anna Lövqvist, Jonas Malmqvist, Pär Olsson, Magnus Essand, Jan Pontén, Stefan Sjöb

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1994

Language:

english

File:

PDF, 2.12 MB

english, 1994

19

Strategic use of an adenoviral vector for rapid and efficient ex vivo-generation of cytomegalovirus pp65-reactive cytolytic and helper T cells

Ole Forsberg, Björn Carlsson, Thomas H. Tötterman, Magnus Essand

Journal:

British Journal of Haematology

Year:

2008

Language:

english

File:

PDF, 498 KB

english, 2008

20

The immunotherapy of prostate and bladder cancer

Thomas H. Totterman, Angelica Loskog, Magnus Essand

Journal:

BJU International

Year:

2005

Language:

english

File:

PDF, 152 KB

english, 2005

21

An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

Danielsson, A, Elgue, G, Nilsson, B M, Nilsson, B, Lambris, J D, Tötterman, T H, Kochanek, S, Kreppel, F, Essand, M

Journal:

Year:

2010

Language:

english

File:

PDF, 765 KB

english, 2010

22

Oncolytic adenovirus modified with somatostatin motifs for selective infection of neuroendocrine tumor cells

Leja, J, Yu, D, Nilsson, B, Gedda, L, Zieba, A, Hakkarainen, T, Åkerström, G, Öberg, K, Giandomenico, V, Essand, M

Journal:

Year:

2011

Language:

english

File:

PDF, 856 KB

english, 2011

23

Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas

Leja, Justyna, Essaghir, Ahmed, Essand, Magnus, Wester, Kenneth, öberg, Kjell, Tötterman, Thomas H, Lloyd, Ricardo, Vasmatzis, George, Demoulin, Jean-Baptiste, Giandomenico, Valeria

Journal:

Modern Pathology

Year:

2008

Language:

english

File:

PDF, 373 KB

english, 2008

24

An oncolytic conditionally replicating adenovirus for hormone-dependent and hormone-independent prostate cancer

Cheng, W-S, Dzojic, H, Nilsson, B, Tötterman, T H, Essand, M

Journal:

Cancer Gene Therapy

Year:

2005

Language:

english

File:

PDF, 318 KB

english, 2005

25

Two-step amplification of the human PPT sequence provides specific gene expression in an immunocompetent murine prostate cancer model

Dzojic, H, Cheng, W-S, Essand, M

Journal:

Cancer Gene Therapy

Year:

2006

Language:

english

File:

PDF, 212 KB

english, 2006

26

Increased therapeutic efficacy of the prostate-specific oncolytic adenovirus Ad[I/PPT-E1A] by reduction of the insulator size and introduction of the full-length E3 region

Danielsson, A, Dzojic, H, Nilsson, B, Essand, M

Journal:

Cancer Gene Therapy

Year:

2008

Language:

english

File:

PDF, 314 KB

english, 2008

27

Identification of Three New Alternate Human Kallikrein 2 Transcripts: Evidence of Long Transcript and Alternative Splicing

Xiu Fen Liu, Magnus Essand, George Vasmatzis, Byungkook Lee, Ira Pastan

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 281 KB

english, 1999

28

Genetically engineered T cells for the treatment of cancer

Essand, M., Loskog, A. S. I.

Journal:

Journal of Internal Medicine

Year:

2013

Language:

english

File:

PDF, 451 KB

english, 2013

29

An Infection-enhanced Oncolytic Adenovirus Secreting H. pylori Neutrophil-activating Protein with Therapeutic Effects on Neuroendocrine Tumors

Ramachandran, Mohanraj, Yu, Di, Wanders, Alkwin, Essand, Magnus, Eriksson, Fredrik

Journal:

Molecular Therapy

Year:

2013

Language:

english

File:

PDF, 5.32 MB

english, 2013

30

Irregular variations in radiation sensitivity when the linear energy transfer is increased

Stenerlöw, Bo, Pettersson, Orn-Anong, Essand, Magnus, Blomquist, Erik, Carlsson, Jörgen

Journal:

Radiotherapy and Oncology

Year:

1995

Language:

english

File:

PDF, 895 KB

english, 1995

31

Discovery of Three Genes Specifically Expressed in Human Prostate by Expressed Sequence Tag Database Analysis

George Vasmatzis, Magnus Essand, Ulrich Brinkmann, Byungkook Lee and Ira Pastan

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.33 MB

english, 1998

32

PAGE-1, an X Chromosome-Linked GAGE-Like Gene that is Expressed in Normal and Neoplastic Prostate, Testis, and Uterus

Ulrich Brinkmann, George Vasmatzis, Byungkook Lee, Noga Yerushalmi, Magnus Essand and Ira Pastan

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.45 MB

english, 1998

33

High Expression of a Specific T-Cell Receptor γ Transcript in Epithelial Cells of the Prostate

Magnus Essand, George Vasmatzis, Ulrich Brinkmann, Paul Duray, Byungkook Lee and Ira Pastan

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.40 MB

english, 1999

34

Preclinical Safety Assessment of Ad[I/PPT-E1A], a Novel Oncolytic Adenovirus for Prostate Cancer

Schenk, Ellen, Essand, Magnus, Kraaij, Robert, Adamson, Rachel, Maitland, Norman J., Bangma, Chris H.

Journal:

Human Gene Therapy Clinical Development

Year:

2014

Language:

english

File:

PDF, 413 KB

english, 2014

35

Clinical Adenoviral Gene Therapy for Prostate Cancer

Schenk, Ellen, Essand, Magnus, Bangma, Chris H.

Journal:

Human Gene Therapy

Year:

2010

Language:

english

File:

PDF, 105 KB

english, 2010

36

Vector-Encoded Helicobacter pylori Neutrophil-Activating Protein Promotes Maturation of Dendritic Cells with Th1 Polarization and Improved Migration

Ramachandran, M., Jin, C., Yu, D., Eriksson, F., Essand, M.

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 1.35 MB

english, 2014

37

Gene expression in midgut carcinoid tumors: Potential targets for immunotherapy

Vikman, Sofia, Essand, Magnus, Cunningham, Janet L., Torre, Manuel de la, Öberg, Kjell, Tötterman, Thomas H., Giandomenico, Valeria

Journal:

Acta Oncologica

Year:

2005

Language:

english

File:

PDF, 284 KB

english, 2005

38

E4, A New Monoclonal Antibody Identifying a Human Prostatic Cell Surface Antigen

Nilsson, Sten, Essand, Magnus, Lögdahl, Pia, Larson, Anders, Nordgren, Hans, Juhlin, Claes

Journal:

Cancer Biotherapy & Radiopharmaceuticals

Year:

1997

Language:

english

File:

PDF, 3.42 MB

english, 1997

39

Combining CAR T cells and the Bcl-2 family apoptosis inhibitor ABT-737 for treating B-cell malignancy

Karlsson, S C H, Lindqvist, A C, Fransson, M, Paul-Wetterberg, G, Nilsson, B, Essand, M, Nilsson, K, Frisk, P, Jernberg-Wiklund, H, Loskog, S I A

Journal:

Cancer Gene Therapy

Year:

2013

Language:

english

File:

PDF, 582 KB

english, 2013

40

In Vitro Primary Cell Culture as a Physiologically Relevant Method for Preclinical Testing of Human Oncolytic Adenovirus

Adamson, R.E., Frazier, A.A., Evans, H., Chambers, K.F., Schenk, E., Essand, M., Birnie, R., Mitry, R.R., Dhawan, A., Maitland, N.J.

Journal:

Human Gene Therapy

Year:

2012

Language:

english

File:

PDF, 1.17 MB

english, 2012

41

Gene Transfer Vectors Targeted to Human Prostate Cancer: Do We Need Better Preclinical Testing Systems?

Maitland, Norman, Chambers, Karen, Georgopoulos, Lindsay, Simpson-Holley, Martha, Leadley, Regina, Evans, Helen, Essand, Magnus, Danielsson, Angelika, van Weerden, Wytske, de Ridder, Corrina, Kraaij,

Journal:

Human Gene Therapy

Year:

2010

Language:

english

File:

PDF, 25.17 MB

english, 2010

42

1025. A PPT Promoter-Based Adenovirus with Two-Step Transcriptional Amplification (TSTA) for Experimental Prostate Cancer

DZOJIC, H, CHENG, W, ESSAND, M

Journal:

Molecular Therapy

Year:

2005

Language:

english

File:

PDF, 88 KB

english, 2005

43

1024. An Oncolytic Conditionally Replicating Adenovirus for Hormone-Dependent and Hormone-Independent Prostate Cancer

CHENG, W, DZOJIC, H, NILSSON, B, TOTTERMAN, T, ESSAND, M

Journal:

Molecular Therapy

Year:

2005

Language:

english

File:

PDF, 88 KB

english, 2005

44

649. Increased Therapeutic Efficacy of the Prostate-Specific Oncolytic Adenovirus Ad[I/PPT-E1A] by Introduction of the Entire E3 Region or the Adenovirus Death Protein

Danielsson, Angelika, Dzojic, Helena, Nilsson, Berith, Cheng, Wing-Shing, Essand, Magnus

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 89 KB

english, 2006

45

281. Adenovirus-Mediated CD40 Ligand Therapy Induces Tumor Cell Apoptosis and Systemic Immunity in the TRAMP-C2 Mouse Prostate Cancer Model

Dzojic, Helena, Loskog, Angelica, Totterman, Thomas, Essand, Magnus

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

46

Adenovirus CD40 Ligand Gene Therapy Counteracts Immune Escape Mechanisms in the Tumor Microenvironment

Loskog, A., Dzojic, H., Vikman, S., Ninalga, C., Essand, M., Korsgren, O., Totterman, T. H.

Journal:

The Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 597 KB

english, 2004

47

TARP: A nuclear protein expressed in prostate and breast cancer cells derived from an alternate reading frame of the T cell receptor gamma chain locus

Wolfgang, C. D., Essand, M., Vincent, J. J., Lee, B., Pastan, I.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 241 KB

english, 2000

48

A Hexon and Fiber-modified Adenovirus Expressing CD40L Improves the Antigen Presentation Capacity of Dendritic Cells

Liljenfeldt, Lina, Yu, Di, Chen, Liye, Essand, Magnus, Mangsbo, Sara M.

Journal:

Journal of Immunotherapy

Year:

2014

Language:

english

File:

PDF, 582 KB

english, 2014

49

T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2+ prostate and breast cancer cells

Hillerdal, V., Nilsson, B., Carlsson, B., Eriksson, F., Essand, M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2012

Language:

english

File:

PDF, 311 KB

english, 2012

50

Macrophage Delivery of an Oncolytic Virus Abolishes Tumor Regrowth and Metastasis after Chemotherapy or Irradiation

Muthana, M., Rodrigues, S., Chen, Y.-Y., Welford, A., Hughes, R., Tazzyman, S., Essand, M., Morrow, F., Lewis, C. E.

Journal:

Cancer Research

Year:

2013

Language:

english

File:

PDF, 969 KB

english, 2013

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